Quality of Life and Its Contributing Factors in Patients with Familial Hypercholesterolaemia in Malaysia


  • Salmi Razali Department of Psychiatry, Faculty of Medicine, Universiti Teknologi MARA
  • Zaliha Ismail Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA
  • Yung An Chua Institute of Pathology, Laboratory and Forensic Medicine (I-PPerForM) and Faculty of Medicine, Universiti Teknologi MARA, 47000 Sungai Buloh, Selangor, Malaysia
  • Hapizah M Nawawi Institute of Pathology, Laboratory and Forensic Medicine (I-PPerForM) and Faculty of Medicine, Universiti Teknologi MARA, 47000 Sungai Buloh, Selangor, Malaysia




Familial hypercholesterolaemia, quality of life, sociodemography, cardiovascular disease


Familial hypercholesterolaemia (FH) causes severe complications including cardiovascular diseases (CVDs) and stroke, leading to poor quality of life (QoL). Despite the availability of advanced treatment, data on QoL and its contributing factors is sparse. Hence, this study aimed to describe the pattern of QoL among FH patients and investigate its association with sociodemographic factors and illness characteristics. Hundred FH patients were assessed using Pro forma questionnaires and World Health Organization QoL questionnaire (WHOQOL-BREF). Significant contributing factors including level of education, income, and the presence and type of CVDs. These findings may help to inform more effective interventions for FH patients.   

Keywords: Familial hypercholesterolaemia; quality of life; sociodemography; cardiovascular disease

eISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/e-bpj.v4i10.1621


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How to Cite

Razali, S., Ismail, Z., Chua, Y. A., & Nawawi, H. M. (2019). Quality of Life and Its Contributing Factors in Patients with Familial Hypercholesterolaemia in Malaysia. Environment-Behaviour Proceedings Journal, 4(10), 86–92. https://doi.org/10.21834/e-bpj.v4i10.1621

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