Prevalence of Erectile Dysfunction and Quality of Life among Male with Diabetes Mellitus: A systematic review
DOI:
https://doi.org/10.21834/e-bpj.v10i31.6336Keywords:
Prevalence, Quality of life, Erectile Dysfunction, Male, DiabetesAbstract
This systematic review examines the prevalence of Erectile Dysfunction (ED) and its impact on Quality of Life (QoL) among males with diabetes. Following PRISMA guidelines, literature from 2018 to 2024 was analyzed, with 11 relevant studies selected from 172 screened articles. The quality of each study was appraised using the Joanna Briggs Institute checklist, yielding a combined sample size of 3,928 diabetes males. Findings show an ED prevalence range of 28.1% to 94.7%, with ED contributing to lower self-esteem, relationship difficulties, and psychological distress, significantly impacting QoL. The study highlights the need for targeted interventions to improve the QoL of diabetes males in Malaysia.
References
Akhtar, S., Nasir, J. A., Ali, A., Asghar, M., Majeed, R., & Sarwar, A. (2022). Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis. PLoS ONE, 17(1 January), 1–14. https://doi.org/10.1371/journal.pone.0263139 DOI: https://doi.org/10.1371/journal.pone.0263139
Alanazi, B. G., Alshagraawi, S. A., Alobaidi, M., Alturki, N., & Kofi, M. (2022). Impact of Shift Work on Sleep and the Quality of Life of Healthcare Workers in Saudi Arabia. Family Medicine and Primary Care: Open Access, 6(2). https://doi.org/10.29011/2688-7460.100076 DOI: https://doi.org/10.29011/2688-7460.100076
Alaofè H, Amoussa W, Djrolo F, Ehiri J, & Rosales C. (2022). Factors Associated with Quality of Life in Patients with Type 2 Diabetes of South Benin: A Cross-Sectional Study. Int J Environ Res Public Health [revista en Internet] 2022 [acceso 2 de abril de 2022]; 19(4): 1-13. International Journal of Environmental Research and Public Health, 19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871979/ DOI: https://doi.org/10.3390/ijerph19042360
Almigbal, T. H. (2019). Erectile dysfunction in men with type 2 diabetes: Is it associated with poor glycemic control? Journal of Men’s Health, 15(1), e12–e22. https://doi.org/10.22374/jomh.v15i1.104 DOI: https://doi.org/10.22374/jomh.v15i1.104
Anwar, Z., Sinha, V., Mitra, S., Mishra, A. K., & Ansari, M. H. (2017). Original Article Erectile Dysfunction : An Underestimated Presentation in Patients with Diabetes Mellitus. https://doi.org/10.4103/0253-7176.217015 DOI: https://doi.org/10.4103/0253-7176.217015
Arunah Chandran, Mohd Nazri Abdullah, F. A. (2019). National Diabetes Registry Report 2013-2019. Disease Control Division Ministry of Health Malaysia, 1–34. http://www.aafp.org/afp/2006/0915/p971.html%5Cnhttp://search.proquest.com/docview/216298826?accountid=15115%5Cnhttp://ndep.nih.gov/media/youth_factsheet.pdf
Barnard-Kelly, K., Meeking, D., Cummings, M., Reidy, C., Scibilia, R., Aldred, C., & Naranjo, D. (2019). Diabetes and male sexual health: an unmet challenge. Practical Diabetes, 36(6), 201–206. https://doi.org/10.1002/pdi.2246 DOI: https://doi.org/10.1002/pdi.2246
Bekele, F., Fantahun, L., Garbessa, B., & Dekosa, F. (2022). Men’s sexual desire, and why women often don’t recognize it? Prevalence of erectile dysfunction and associated factors among diabetes mellitus patients attending Mettu Karl Comprehensive Specialized Hospital: A cross-sectional study. SAGE Open Medicine, 10. https://doi.org/10.1177/20503121221141803 DOI: https://doi.org/10.1177/20503121221141803
de Silva, N. L., Athukorala, T., Gamage, J. L., Katulanda, G., de Silva, P., Sumanatilleke, M., & Somasundaram, N. (2022). Sexual dysfunction among men with diabetes; a cross-sectional study at a specialised diabetes clinic in Sri Lanka. BMC Endocrine Disorders, 22(1), 1–9. https://doi.org/10.1186/s12902-022-01108-1 DOI: https://doi.org/10.1186/s12902-022-01108-1
Defeudis, G., Mazzilli, R., Scandurra, C., Di Tommaso, A. M., Cimadomo, D., Strollo, R., Faggiano, A., Migliaccio, S., & Napoli, N. (2023). Diabetes and erectile dysfunction: The relationships with health literacy, treatment adherence, unrealistic optimism, and glycaemic control. Diabetes/Metabolism Research and Reviews, 39(5). https://doi.org/10.1002/dmrr.3629 DOI: https://doi.org/10.1002/dmrr.3629
Fang, Y., Dong, Z., Huang, T., Wang, L., Fan, W., Wang, B., Yang, Q., Xu, M., Li, D., Fang, Y., & Xu, Z. (2023). The role of socioeconomic status and oxidative balance score in erectile dysfunction: A cross-sectional study. Heliyon, 9(11), e22233. https://doi.org/10.1016/j.heliyon.2023.e22233 DOI: https://doi.org/10.1016/j.heliyon.2023.e22233
Gebeyehu, N. A., Gesese, M. M., Tegegne, K. D., Kebede, Y. S., Kassie, G. A., Mengstie, M. A., Zemene, M. A., Bantie, B., Feleke, S. F., Dejenie, T. A., Abebe, E. C., Anley, D. T., Dessie, A. M., Bayih, W. A., & Adela, G. A. (2023). Global prevalence of sexual dysfunction among diabetic patients from 2008 to 2022: Systematic review and meta-analysis. Metabolism Open, 18(May), 100247. https://doi.org/10.1016/j.metop.2023.100247 DOI: https://doi.org/10.1016/j.metop.2023.100247
Haddaway, N. R., Page, M. J., Pritchard, C. C., & McGuinness, L. A. (2022). PRISMA2020: An R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis. Campbell Systematic Reviews, 18(2), 1–12. https://doi.org/10.1002/cl2.1230 DOI: https://doi.org/10.1002/cl2.1230
Hylmarova, S., Stechova, K., Pavlinkova, G., Peknicova, J., Macek, M., & Kvapil, M. (2020). The impact of type 1 diabetes mellitus on male sexual functions and sex hormone levels. Endocrine Journal, 67(1), 59–71. https://doi.org/10.1507/endocrj.EJ19-0280 DOI: https://doi.org/10.1507/endocrj.EJ19-0280
Jombo, H. E., Onung, S. I., Idung, A. U., & Iyanam, V. E. (2020). Erectile Dysfunction and Depression in Males with Type 2 Diabetes Mellitus in a Tertiary Healthcare Facility in Uyo, South-South Nigeria. Asian Journal of Medical Principles and Clinical Practice, 3(1), 9–17. https://journalajmpcp.com/index.php/AJMPCP/article/view/32
Kang, W. H., Mohamad Sithik, M. N., Khoo, J. K., Ooi, Y. G., Lim, Q. H., & Lim, L. L. (2022). Gaps in the management of diabetes in Asia: A need for improved awareness and strategies in men’s sexual health. In Journal of Diabetes Investigation (Vol. 13, Issue 12, pp. 1945–1957). Wiley-Blackwell. https://doi.org/10.1111/jdi.13903 DOI: https://doi.org/10.1111/jdi.13903
Katsimardou, A., Patoulias, D., Zografou, I., Tegou, Z., Imprialos, K., Stavropoulos, K., Toumpourleka, M., Karagiannis, A., Petidis, K., & Doumas, M. (2023). The Associations between Kidney Function and Sexual Dysfunction among Males and Females with Type 2 Diabetes Mellitus. Medicina (Lithuania), 59(5). https://doi.org/10.3390/medicina59050969 DOI: https://doi.org/10.3390/medicina59050969
Monnaatsie, M., Biddle, S. J. H., Khan, S., & Kolbe-Alexander, T. (2021). Physical activity and sedentary behaviour in shift and non-shift workers: A systematic review and meta-analysis. Preventive Medicine Reports, 24, 101597. https://doi.org/10.1016/j.pmedr.2021.101597 DOI: https://doi.org/10.1016/j.pmedr.2021.101597
Moola, S., Munn, Z., Sears, K., Sfetcu, R., Currie, M., Lisy, K., Tufanaru, C., Qureshi, R., Mattis, P., & Mu, P. (2015). Conducting systematic reviews of association (etiology): The Joanna Briggs Institute’s approach. International Journal of Evidence-Based Healthcare, 13(3), 163 169. https://doi.org/10.1097/XEB.0000000000000064 DOI: https://doi.org/10.1097/XEB.0000000000000064
Mushtaq, S., Khan, K., Abid, S., Umer, A., & Raza, T. (2018). Frequency of Hypogonadism and Erectile Dysfunction in Type-II Diabetic Patients. Cureus, 10(5). https://doi.org/10.7759/cureus.2654 DOI: https://doi.org/10.7759/cureus.2654
Ndang Ngou Milama, S., Mougougou, A., Olagui, S. G., Mbethe, D., Nsame, D., Boundama, H. G., & Ngoungou, B. E. (2022). Analysis of the Factors Associated With ED in Type 2 Diabetics at the University Hospital of Libreville. Sexual Medicine, 10(6), 100564. https://doi.org/10.1016/j.esxm.2022.100564 DOI: https://doi.org/10.1016/j.esxm.2022.100564
Organization.Diabetes, W. H. (2023). Diabetes 5. World Health Organization.
Przydacz, M., Chlosta, M., Rajwa, P., & Chlosta, P. (2023). Population-level prevalence, effect on quality of life, and treatment behavior for erectile dysfunction and premature ejaculation in Poland. Scientific Reports, 13(1), 1–12. https://doi.org/10.1038/s41598-023-39968-9 DOI: https://doi.org/10.1038/s41598-023-39968-9
Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997). The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction. Urology, 49(6), 822–830. https://doi.org/10.1016/S0090-4295(97)00238-0 DOI: https://doi.org/10.1016/S0090-4295(97)00238-0
Schweyer, L. (2017). Diabetes and quality of life. Revue de l’Infirmiere, 64(211), 45–46. https://doi.org/10.1016/j.revinf.2015.02.017 DOI: https://doi.org/10.1016/j.revinf.2015.02.017
Sondhi, M., Kakar, A., Gogia, A., & Gupta, M. (2018). Prevalence of erectile dysfunction in diabetic patients. Current Medicine Research and Practice, 8(3), 88–91. https://doi.org/10.1016/j.cmrp.2018.05.005 DOI: https://doi.org/10.1016/j.cmrp.2018.05.005
Thongtang, P., Fongkaew, W., Lojanapiwat, B., Sansiriphun, N., & Chaloumsuk, N. (2020). Prevalence and factors associated with quality of life among diabetic men living with erectile dysfunction. Walailak Journal of Science and Technology, 17(9), 947–957. https://doi.org/10.48048/wjst.2020.5336 DOI: https://doi.org/10.48048/wjst.2020.5336
Torkamani, Z. J., Dolatian, M., Omani-Samani, R., Alizadeh, A., & Navid, B. (2021). Relationship between sexual function and type 2 diabetes in infertile men referred to Royan institute. Journal of Renal Injury Prevention, 10(4), 1–7. https://doi.org/10.34172/jrip.2021.33 DOI: https://doi.org/10.34172/jrip.2021.33
Ugwumba, F. O., Okafor, C. I., Nnabugwu, I. I., Udeh, E. I., Echetabu, K. N., Okoh, A. D., & Okorie, J. C. (2018). Prevalence of, and risk factors for erectile dysfunction in male type 2 diabetic outpatient attendees in Enugu, South East Nigeria. Annals of African Medicine, 17(4), 215 220. https://doi.org/10.4103/aam.aam_3_18 DOI: https://doi.org/10.4103/aam.aam_3_18
Walle, B., Lebeta, K. R., Fita, Y. D., & Abdissa, H. G. (2018). Prevalence of erectile dysfunction and associated factors among diabetic men attending the diabetic clinic at Felege Hiwot Referral Hospital, Bahir Dar, North West Ethiopia, 2016. BMC Research Notes, 11(1), 1–5. https://doi.org/10.1186/s13104-018-3211-2 DOI: https://doi.org/10.1186/s13104-018-3211-2
Yafi, F. A., Jenkins, L., Albersen, M., Corona, G., Isidori, A. M., Goldfarb, S., Maggi, M., Nelson, C. J., Parish, S., Salonia, A., Tan, R., Mulhall, J. P., & Hellstrom, W. J. G. (2016). Erectile dysfunction. Nature Reviews Disease Primers, 2(1). https://doi.org/10.1038/NRDP.2016.3 DOI: https://doi.org/10.1038/nrdp.2016.3
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Jheffany Yazid , Suzana Yusof , Siti Khuzaimah Ahmad Sharoni , Angga Wilandika

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.